brain membranes — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1909	L-701324	L701324	NMDAR , iGluR
	L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.		NMDAR , iGluR
T5518	N-acetylcysteine amide		Reactive Oxygen Species , ROS
	N-Acetylcysteine amide is a thiol antioxidant and neuroprotective agent that can permeate cell membranes and the blood-brain barrier.		Reactive Oxygen Species , ROS
T33604	Z-Glycine	Carbobenzoxyglycine,N-Carbobenzoxyglycine	Others
	Z-Glycine (Carbobenzoxyglycine) is a drug-lipid conjugates designed to promote brain penetration based on its lipophilicity and resemblance to lipids in biological membranes[1].		Others
T10162	5-HT3 antagonist 3		5-HT Receptor
	5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM).		5-HT Receptor
T6352	(-)-Dizocilpine maleate	C13737,(-)-MK 801 (Maleate),(-)-MK 801 Maleate	NMDAR , iGluR
	(-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.		NMDAR , iGluR
T15632	JW 642		Lipase
	JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).		Lipase
T13423	(1R,2R)-2-PCCA hydrochloride	(1R,2R)-2-PCCA(hydrochloride)	Others
	(1R,2R)-2-PCCA hydrochloride is a potent, selective, and blood-brain-barrier-crossing GPR88 receptor agonist with an EC50 value of 1140 n in striatal membranes of WT mice.(1R,2R)-2-PCCA hydrochloride can be used to study...		Others
T23394	SR 57227A	SR 57227 hydrochloride	5-HT Receptor
	SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier. It has affinities (IC50) varying between 2.8 and 250 nM for 5-HT3 rece...		5-HT Receptor
T6554	JZL 184	JZL184	Lipase
	JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively.		Lipase
T38140	Phosphatidylethanolamine from bovine
	Phosphatidylethanolamines (bovine) are a mixture of phosphatidylethanolamines isolated from bovine brain with different fatty acyl groups at the sn-1 and sn-2 positions.Phosphatidylethanolamines (bovine) are the most abu...
TP1940L1	Ac-RYYRIK-NH2 acetate		Opioid Receptor
	Ac-RYYRIK-NH2 acetate is an agonist at nociceptin/orphanin FQ(noc/OFQ) receptors, affecting spontaneous locomotor activity. Ac-RYYRIK-NH2 acetate is a partial agonist on ORL1 transfected in CHO cells, antagonizes the sti...		Opioid Receptor
T3320	Dizocilpine Maleate	(+)-Mk-801 Hydrogen Maleate,MK 801,Dizocilpine hydrogen maleate,(+)-MK 801 maleate,(+)-MK 801 (Maleate)	NMDAR , iGluR
	Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membranes. The drug has been considered for the wide variety of ne...		NMDAR , iGluR
T23445	Anxiolytic/nonsedative agent-1	TCS 1205	GABA Receptor
	Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α...		GABA Receptor
T19686	SCH-37370		Platelet aggregation
	SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectiv...		Platelet aggregation
T22744	DPCPX	PD 116948	Adenosine Receptor
	DPCPX (PD 116948) is an A1 adenosine receptor antagonist		Adenosine Receptor
T32423	KS 5-2	KS-5-2
	KS 5-2 has affinity to isolated synaptic membranes from rat brain.
T68874	Kojic amine
	Kojic amine is a GABA receptor agonist; potent and specific inhibitor of Na+-independent GABA binding to rat brain membranes.
T23587	8-CSC	8 CSC,CSC
	8-CSC is a dual agent endowed with good hMAO-B inhibitory activity (Ki: 235 nM in baboon liver mitochondria) and A2A affinity (Ki: 36 nM in rat brain striatal membranes receptor).
T71987	5-hydroxy Isatin
	5-hydroxy Isatin is an inhibitor of monoamine oxidase A and also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.
T40445	Cyclocreatine
	Cyclocreatine, a Creatine analogue, exhibits potent bioenergetic protection by elevating ATP levels. It demonstrates the ability to traverse cell membranes, including the blood-brain barrier, wherein it undergoes phospho...